CYCLODEXTRINS, THEIR PROPERTIES AND USES OF Β-CYCLODEXTRIN IN DIFFERENT INDUSTRIES: A REVIEW

Abstract

Cyclodextrins are a family of cyclic oligosaccharides composed of α-(1,4) linked glucopyranose subunits. All cyclodextrins are produced due to the transformation of starch by the bacteria e.g. Bacillus macerans. This whole procedure comprises of 4 phases.  There are three basic types of cyclodextrinsnamely Alpha, beta and gamma cyclodextrins. Upon I.V injection the alpha-cyclodextrin is the most irritatating. There is a directly effect of temperature on solubility of cyclodextrins as the temperature increases the solubility increases. All cyclodextrins are heat stable and are non hygroscopic in nature. These are chemically stable compounds and are hydrolyzed by cyclodextringlucosyltransferase (CGT-ase) the enzyme used to produce cyclodextrins.Complexes are typically formed with organic compounds and these complex formations are either reversible or irreversible.Among all three types beta cyclodextrins and their derivatives are widely used in different industries due to their some distinguished properties e.g. most accessible, the lowest-priced, less irritating, and diameter etc. The major industrial uses of beta cyclodextrins and their derivatives includes in cosmetology, in food industry, in laundry, as deodorants, tobacco industries, decrease in undesirable effects, increase solubility, prolonged release of active ingredients.