The Role of Immune Cells in the Tumor Microenvironment

Abstract

The tumor microenvironment (TME) is a complex and dynamic ecosystem that plays a pivotal role in cancer development and progression. Within this intricate milieu, immune cells are central players, exerting both pro- and anti-tumorigenic effects. This comprehensive paper explores the multifaceted roles of immune cells in the TME, shedding light on their interactions, functions, and potential therapeutic implications. We delve into the diversity of immune cell types, their recruitment, and the mechanisms underlying their activities in shaping the TME. Additionally, we discuss emerging immunotherapeutic strategies that harness the power of immune cells to combat cancer. This in-depth analysis underscores the pivotal role of immune cells in the TME and highlights their potential as targets for novel cancer therapies.